Where is the only way to upgrade the profits of chemical API?
Release Time: 2018-11-15 09:57:16 Visited: 6531 times
API is the active ingredient in the drug which plays a pharmacological role. API and excipients together constitute the drug preparation for clinical application. As one of the strategic pillars of China's pharmaceutical industry, chemical API industry has formed a relatively complete industrial system through decades of development, and has the characteristics of large scale, low cost and high output. In recent years, with the transfer of international chemical API industry, China has become one of the largest API producing countries in the world.
According to the data released by the National Bureau of statistics on May 15, the investment in chemical raw materials and chemical products manufacturing industry from January to April 2017 was 343.7 billion yuan, up 2.2% year on year. In addition, according to the website of the Ministry of industry and information technology, chemical API was the fastest growing enterprise in the pharmaceutical industry in 2016.
Chemical raw materials refer to the raw materials used in the production of various preparations. They are the active ingredients in preparations. They are all kinds of powders, crystals, extracts, etc. prepared by chemical synthesis, plant extraction or biotechnology and used as medicinal materials, but cannot be taken directly by patients. Chemical API manufacturing refers to the production of API for further processing of pharmaceutical preparations, which belongs to the pharmaceutical manufacturing industry.
China's chemical API industry has begun to transform from the production of extensive low-end intermediates to fine high-end products. It is a big country in the production of chemical APIs and pharmaceutical intermediates. However, compared with the developed countries in the pharmaceutical industry, there is a certain gap in terms of production technology level and research and development concept. China's chemical API industry is still at the bottom of the value chain of the international pharmaceutical industry, and industrial upgrading is the only way. Among them, the quality of drying equipment is also closely related to the upgrading of API. Industry insiders said that reasonable selection of drying equipment can improve the drying efficiency of API.
It is understood that in recent years, the level of drying equipment in China has made great progress, mainly in the following aspects: ① the allocation of control system. Automatic and semi-automatic control system is widely used, which reduces labor intensity and stabilizes product quality. ② The application of computer technology. In most large-scale systems, computer technology is used to collect, process and control system parameters, so as to optimize the system operation conditions. ③ Humanized design. In the design of the equipment, the operator's habits and the convenience of maintenance should be considered. ④ Safety design. The system has the functions of safety alarm and danger elimination, especially the drying of flammable and explosive materials. ⑤ Accessory equipment. The auxiliary equipment in the system also tends to be reasonable, and the matching relationship between heating, feeding, gas-solid separation, product packaging equipment and the host is optimized. Improving the technical level of drying equipment is one of the key equipment to improve the quality of API.
China is a big country of API production, but it is not a powerful country of API production. There are many reasons for this, but one of the most important reasons is that there is a certain gap between the production of API equipment and the application of new technology and the international high-end level. Therefore, in order to improve the quality level of API production in China, we should not only improve the control standards of production enterprises in terms of software and hardware, but also strengthen the application of new technologies of API equipment according to the new changes in the global market, so as to truly integrate with international standards.
Industry insiders said that the "online" in the pharmaceutical production process is inseparable from the real-time production. In order to be "online", we must rely on automation technology and its application to realize real-time detection and process control.